Company · CIK 1503802 # Karyopharm Therapeutics Inc. | CIK | [1503802](https://www.sec.gov/cgi-bin/browse-edgar?action=getcompany&CIK=0001503802) (SEC EDGAR) | | --- | --- | | Industry (SIC) | 2834 — Pharmaceutical Preparations | | Incorporated in | DE | | Business address | MA | | Listed | KPTI (Nasdaq) | | First annual or quarterly report | 2013-12-20 | ## Offerings 16 registrations | Registration | Label and status | First filed | Last event | Filings | | --- | --- | --- | --- | --- | | 333-295533 | Shelf Effective | 2026-05-04 | 2026-05-14 | 2 | | 333-295535 | Shelf Effective | 2026-05-04 | 2026-05-14 | 2 | | 333-291223 | Shelf Dormant | 2025-11-03 | 2025-11-03 | 1 | | 333-291224 | Shelf Dormant | 2025-11-03 | 2025-11-03 | 1 | | 333-279833 | Shelf Effective | 2024-05-30 | 2024-06-07 | 2 | | 333-269846 | Shelf Effective | 2023-02-17 | 2023-05-05 | 2 | | 333-268991 | Shelf Effective | 2022-12-23 | 2023-01-03 | 2 | | 333-258500 | Shelf Effective | 2021-08-05 | 2021-08-05 | 1 | | 333-236639 | Shelf Effective | 2020-02-26 | 2020-05-05 | 4 | | 333-226038 | Shelf Effective | 2018-07-02 | 2019-05-10 | 4 | | 333-222726 | Shelf Effective | 2018-01-26 | 2018-05-03 | 4 | | 333-214489 | Shelf Effective | 2016-11-08 | 2017-12-01 | 5 | | 333-201366 | Shelf Effective | 2015-01-05 | 2016-11-08 | 7 | | 333-196892 | Registered company Final prospectus | 2014-06-19 | 2014-06-27 | 4 | | 333-194750 | Registered company Withdrawn | 2014-03-24 | 2014-04-07 | 2 | | 333-191584 | IPO Final prospectus | 2013-10-04 | 2013-11-07 | 4 | ## Filings 48 | Filed | Filing | Registration | Accession | | --- | --- | --- | --- | | 2026-05-14 | [EFFECT](https://www.sec.gov/Archives/edgar/data/1503802/999999999526001656/9999999995-26-001656-index.htm) Declared effective | 333-295535 | 9999999995-26-001656 | | 2026-05-14 | [EFFECT](https://www.sec.gov/Archives/edgar/data/1503802/999999999526001655/9999999995-26-001655-index.htm) Declared effective | 333-295533 | 9999999995-26-001655 | | 2026-05-04 | [S-3](https://www.sec.gov/Archives/edgar/data/1503802/000119312526204134/0001193125-26-204134-index.htm) Shelf registered | 333-295535 | 0001193125-26-204134 | | 2026-05-04 | [S-3](https://www.sec.gov/Archives/edgar/data/1503802/000119312526204130/0001193125-26-204130-index.htm) Shelf registered | 333-295533 | 0001193125-26-204130 | | 2025-11-03 | [S-3](https://www.sec.gov/Archives/edgar/data/1503802/000119312525262581/0001193125-25-262581-index.htm) Shelf registered | 333-291224 | 0001193125-25-262581 | | 2025-11-03 | [S-3](https://www.sec.gov/Archives/edgar/data/1503802/000119312525262571/0001193125-25-262571-index.htm) Shelf registered | 333-291223 | 0001193125-25-262571 | | 2024-06-07 | [EFFECT](https://www.sec.gov/Archives/edgar/data/1503802/999999999524001788/9999999995-24-001788-index.htm) Declared effective | 333-279833 | 9999999995-24-001788 | | 2024-05-30 | [S-3](https://www.sec.gov/Archives/edgar/data/1503802/000119312524150438/0001193125-24-150438-index.htm) Shelf registered | 333-279833 | 0001193125-24-150438 | | 2023-05-05 | [EFFECT](https://www.sec.gov/Archives/edgar/data/1503802/999999999523001314/9999999995-23-001314-index.htm) Declared effective | 333-269846 | 9999999995-23-001314 | | 2023-02-17 | [S-3](https://www.sec.gov/Archives/edgar/data/1503802/000119312523041600/0001193125-23-041600-index.htm) Shelf registered | 333-269846 | 0001193125-23-041600 | | 2023-01-03 | [EFFECT](https://www.sec.gov/Archives/edgar/data/1503802/999999999523000026/9999999995-23-000026-index.htm) Declared effective | 333-268991 | 9999999995-23-000026 | | 2022-12-23 | [S-3](https://www.sec.gov/Archives/edgar/data/1503802/000119312522311793/0001193125-22-311793-index.htm) Shelf registered | 333-268991 | 0001193125-22-311793 | | 2021-08-05 | [S-3ASR](https://www.sec.gov/Archives/edgar/data/1503802/000119312521237843/0001193125-21-237843-index.htm) Shelf registered | 333-258500 | 0001193125-21-237843 | | 2020-05-05 | [424B5](https://www.sec.gov/Archives/edgar/data/1503802/000119312520133834/0001193125-20-133834-index.htm) Shelf takedown | 333-236639 | 0001193125-20-133834 | | 2020-03-04 | [424B5](https://www.sec.gov/Archives/edgar/data/1503802/000119312520061630/0001193125-20-061630-index.htm) Shelf takedown | 333-236639 | 0001193125-20-061630 | | 2020-03-02 | [424B5](https://www.sec.gov/Archives/edgar/data/1503802/000119312520058937/0001193125-20-058937-index.htm) Shelf takedown | 333-236639 | 0001193125-20-058937 | | 2020-02-26 | [S-3ASR](https://www.sec.gov/Archives/edgar/data/1503802/000119312520049253/0001193125-20-049253-index.htm) Shelf registered | 333-236639 | 0001193125-20-049253 | | 2019-05-10 | [424B5](https://www.sec.gov/Archives/edgar/data/1503802/000119312519144258/0001193125-19-144258-index.htm) Shelf takedown | 333-226038 | 0001193125-19-144258 | | 2019-04-24 | [EFFECT](https://www.sec.gov/Archives/edgar/data/1503802/999999999519000812/9999999995-19-000812-index.htm) Declared effective | 333-226038 | 9999999995-19-000812 | | 2018-08-17 | [424B5](https://www.sec.gov/Archives/edgar/data/1503802/000119312518251663/0001193125-18-251663-index.htm) Shelf takedown | 333-226038 | 0001193125-18-251663 | | 2018-07-02 | [S-3ASR](https://www.sec.gov/Archives/edgar/data/1503802/000119312518211350/0001193125-18-211350-index.htm) Shelf registered | 333-226038 | 0001193125-18-211350 | | 2018-05-03 | [424B5](https://www.sec.gov/Archives/edgar/data/1503802/000119312518150953/0001193125-18-150953-index.htm) Shelf takedown | 333-222726 | 0001193125-18-150953 | | 2018-05-01 | [424B5](https://www.sec.gov/Archives/edgar/data/1503802/000119312518146606/0001193125-18-146606-index.htm) Shelf takedown | 333-222726 | 0001193125-18-146606 | | 2018-02-14 | [EFFECT](https://www.sec.gov/Archives/edgar/data/1503802/999999999518000445/9999999995-18-000445-index.htm) Declared effective | 333-222726 | 9999999995-18-000445 | | 2018-01-26 | [S-3](https://www.sec.gov/Archives/edgar/data/1503802/000119312518021593/0001193125-18-021593-index.htm) Shelf registered | 333-222726 | 0001193125-18-021593 | | 2017-12-01 | [424B5](https://www.sec.gov/Archives/edgar/data/1503802/000119312517358965/0001193125-17-358965-index.htm) Shelf takedown | 333-214489 | 0001193125-17-358965 | | 2017-04-26 | [424B5](https://www.sec.gov/Archives/edgar/data/1503802/000119312517139432/0001193125-17-139432-index.htm) Shelf takedown | 333-214489 | 0001193125-17-139432 | | 2017-04-24 | [424B5](https://www.sec.gov/Archives/edgar/data/1503802/000119312517134582/0001193125-17-134582-index.htm) Shelf takedown | 333-214489 | 0001193125-17-134582 | | 2016-12-01 | [EFFECT](https://www.sec.gov/Archives/edgar/data/1503802/999999999516006355/9999999995-16-006355-index.htm) Declared effective | 333-214489 | 9999999995-16-006355 | | 2016-11-08 | [S-3](https://www.sec.gov/Archives/edgar/data/1503802/000119312516761922/0001193125-16-761922-index.htm) Shelf registered | 333-214489 | 0001193125-16-761922 | | 2016-11-08 | [424B5](https://www.sec.gov/Archives/edgar/data/1503802/000119312516761915/0001193125-16-761915-index.htm) Shelf takedown | 333-201366 | 0001193125-16-761915 | | 2016-05-19 | [424B5](https://www.sec.gov/Archives/edgar/data/1503802/000119312516596160/0001193125-16-596160-index.htm) Shelf takedown | 333-201366 | 0001193125-16-596160 | | 2016-05-17 | [EFFECT](https://www.sec.gov/Archives/edgar/data/1503802/999999999516004685/9999999995-16-004685-index.htm) Declared effective | 333-201366 | 9999999995-16-004685 | | 2015-12-08 | [424B5](https://www.sec.gov/Archives/edgar/data/1503802/000119312515396811/0001193125-15-396811-index.htm) Shelf takedown | 333-201366 | 0001193125-15-396811 | | 2015-01-07 | [424B5](https://www.sec.gov/Archives/edgar/data/1503802/000119312515004107/0001193125-15-004107-index.htm) Shelf takedown | 333-201366 | 0001193125-15-004107 | | 2015-01-05 | [424B5](https://www.sec.gov/Archives/edgar/data/1503802/000119312515001868/0001193125-15-001868-index.htm) Shelf takedown | 333-201366 | 0001193125-15-001868 | | 2015-01-05 | [S-3ASR](https://www.sec.gov/Archives/edgar/data/1503802/000119312515001791/0001193125-15-001791-index.htm) Shelf registered | 333-201366 | 0001193125-15-001791 | | 2014-06-27 | [424B4](https://www.sec.gov/Archives/edgar/data/1503802/000104746914005929/0001047469-14-005929-index.htm) Final prospectus | 333-196892 | 0001047469-14-005929 | | 2014-06-26 | [EFFECT](https://www.sec.gov/Archives/edgar/data/1503802/999999999514001949/9999999995-14-001949-index.htm) Declared effective | 333-196892 | 9999999995-14-001949 | | 2014-06-25 | [S-1/A](https://www.sec.gov/Archives/edgar/data/1503802/000104746914005867/0001047469-14-005867-index.htm) Amendment | 333-196892 | 0001047469-14-005867 | | 2014-06-19 | [S-1](https://www.sec.gov/Archives/edgar/data/1503802/000104746914005726/0001047469-14-005726-index.htm) Registration filed | 333-196892 | 0001047469-14-005726 | | 2014-04-07 | [RW](https://www.sec.gov/Archives/edgar/data/1503802/000110465914026197/0001104659-14-026197-index.htm) Withdrawn | 333-194750 | 0001104659-14-026197 | | 2014-03-24 | [S-1](https://www.sec.gov/Archives/edgar/data/1503802/000104746914002819/0001047469-14-002819-index.htm) Registration filed | 333-194750 | 0001047469-14-002819 | | 2013-11-07 | [424B4](https://www.sec.gov/Archives/edgar/data/1503802/000104746913010343/0001047469-13-010343-index.htm) Final prospectus | 333-191584 | 0001047469-13-010343 | | 2013-11-05 | [EFFECT](https://www.sec.gov/Archives/edgar/data/1503802/999999999513003181/9999999995-13-003181-index.htm) Declared effective | 333-191584 | 9999999995-13-003181 | | 2013-10-28 | [S-1/A](https://www.sec.gov/Archives/edgar/data/1503802/000104746913009972/0001047469-13-009972-index.htm) Amendment | 333-191584 | 0001047469-13-009972 | | 2013-10-04 | [S-1](https://www.sec.gov/Archives/edgar/data/1503802/000104746913009519/0001047469-13-009519-index.htm) Registration filed | 333-191584 | 0001047469-13-009519 | | 2013-09-05 | [DRS](https://www.sec.gov/Archives/edgar/data/1503802/000091205713000295/0000912057-13-000295-index.htm) Draft made public | 377-00302 | 0000912057-13-000295 | [All filings of this company](https://equitycapital.markets/filings?cik=1503802) · [CSV](https://equitycapital.markets/filings.csv?cik=1503802) --- Source page: https://equitycapital.markets/company/1503802 · Data: U.S. SEC EDGAR · CC BY 4.0