Company · CIK 2022626

# Upstream Bio, Inc.

| CIK | [2022626](https://www.sec.gov/cgi-bin/browse-edgar?action=getcompany&CIK=0002022626) (SEC EDGAR) |
| --- | --- |
| Industry (SIC) | 2834 — Pharmaceutical Preparations |
| Incorporated in | DE |
| Business address | MA |
| Listed | UPB (Nasdaq) |
| First annual or quarterly report | 2024-11-07 |

## Offerings

 2 registrations

| Registration | Label and status | First filed | Last event | Filings |
| --- | --- | --- | --- | --- |
| 333-291267 | Shelf Effective | 2025-11-05 | 2026-03-26 | 2 |
| 333-282197 | IPO Final prospectus | 2024-09-18 | 2024-10-11 | 4 |

## Filings

 7

| Filed | Filing | Registration | Accession |
| --- | --- | --- | --- |
| 2026-03-26 | [424B5](https://www.sec.gov/Archives/edgar/data/2022626/000119312526126561/0001193125-26-126561-index.htm) Shelf takedown | 333-291267 | 0001193125-26-126561 |
| 2025-11-05 | [S-3ASR](https://www.sec.gov/Archives/edgar/data/2022626/000119312525265752/0001193125-25-265752-index.htm) Shelf registered | 333-291267 | 0001193125-25-265752 |
| 2024-10-11 | [424B4](https://www.sec.gov/Archives/edgar/data/2022626/000119312524236714/0001193125-24-236714-index.htm) Final prospectus | 333-282197 | 0001193125-24-236714 |
| 2024-10-10 | [EFFECT](https://www.sec.gov/Archives/edgar/data/2022626/999999999524003150/9999999995-24-003150-index.htm) Declared effective | 333-282197 | 9999999995-24-003150 |
| 2024-10-07 | [S-1/A](https://www.sec.gov/Archives/edgar/data/2022626/000119312524233296/0001193125-24-233296-index.htm) Amendment | 333-282197 | 0001193125-24-233296 |
| 2024-09-18 | [S-1](https://www.sec.gov/Archives/edgar/data/2022626/000119312524221372/0001193125-24-221372-index.htm) Registration filed | 333-282197 | 0001193125-24-221372 |
| 2024-06-12 | [DRS](https://www.sec.gov/Archives/edgar/data/2022626/000095012324006208/0000950123-24-006208-index.htm) Draft made public | 377-07271 | 0000950123-24-006208 |

[All filings of this company](https://equitycapital.markets/filings?cik=2022626) · [CSV](https://equitycapital.markets/filings.csv?cik=2022626)

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Source page: https://equitycapital.markets/company/2022626 · Data: U.S. SEC EDGAR · CC BY 4.0